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Fibrillation potentials continue until the muscle ber is reinnervated by progressive proximal-distal regeneration of the interrupted nerve ber or by the outgrowth of new axons from nearby healthy nerve bers (collateral sprouting), or until the atrophied bers degenerate and are replaced by connective tissue, a process that may take many years In addition, brillation potentials may take the form of positive sharp waves, ie, spontaneous, initially positive diphasic potentials of longer duration and slightly greater amplitude than the spikes of brillation potentials (see Fig 45-7A) Fibrillation potentials, while characteristic of neurogenic denervation, are not altogether speci c; for example, they are seen in muscle diseases such as polymyositis and inclusion body myositis, which presumably damage the neural innervation to small regions of muscle or isolate segments of a muscle ber from its end plate.

Press z-K or click the Compile button to compile the script, and AppleScript Editor indents the continued line to the next level so that you can more easily see that it is continued:

respectively. You may need to resize the columns or use the scroll bar to view these options. 8. Click the gray bar labeled Date Modi ed; click it again. 9. From the Views drop-down menu, pick List to produce a basic listing of the les.

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Fasciculation Potentials As stated earlier, a fasciculation is the spontaneous or involuntary contraction of a motor unit or part of a motor unit Such contractions may cause a visible dimpling or twitching under the skin, though ordinarily they are of insuf cient force to move a joint Large distal fasciculations, however, can brie y displace a nger or toe; they occur irregularly and infrequently, and prolonged inspection of the skin overlying a muscle may be necessary to detect them The accompanying electrical form of an individual fasciculation potential is relatively constant Typically, a fasciculation potential will have three to ve phases (ie, they are polyphasic as described later, in contrast to normal biphasic muscle activity), a duration of 5 to 15 ms (longer than normal but somewhat less in the facial muscles), and an amplitude of several millivolts (see Fig 45-7B).

GPS consists of three major segments: space, control, and user The space segment consists of the GPS satellites The satellite vehicles (SVs) orbit Earth in six 12-hour (11 hr 58 minute) orbital planes with (nominally) four satellites in each plane The orbits are nearly circular with inclination angles of 55 degrees and altitude above the Earth surface of approximately 20,200 km The six orbit planes are equally spaced around the equator resulting in 60 degree separation This constellation ensures that (barring obstructions) a user located anywhere on Earth has a direct line-of-sight to at least four satellites at any time Since satellites are not in geosynchronous orbits, the geometric relation between the satellites is constantly changing with respect to a stationary receiver on Earth This changing geometry results in changing, but predictable, position estimation accuracy for positions determined from a xed set of satellites (see Section 85).

60-degree-latitude circle is half the size of the equator, or 20,000 kilometers (12,500 miles) around The 90-degree-latitude circles are points with zero circumference Every latitude circle lies in a geometric plane that slices through Earth All these planes are parallel; this is why latitude circles are called parallels Every parallel, except for the poles, consists of infinitely many points, all of which lie on a circle and all of which have the same latitude There is no such thing as a latitude coordinate greater than 90 degrees, either north or south If there were such points, the result would be a redundant set of coordinates The circle representing 100 degrees north latitude would correspond to the 80-degree north-latitude circle, and the circle representing 120 degrees south latitude would correspond to the 60-degree south-latitude circle.

Fasciculation potentials are evidence of motor nerve ber irritability, most often the result of reinnervation following nerve or motor neuron damage Thus, the combination of brillations and fasciculations indicates active denervation combined with more chronic reinnervation of muscle; ie, a long-standing but still ongoing process The precise source of fasciculation is still contested Forster and colleagues, in the 1940s, challenged the original belief that the discharge originated in anterior horn cells by demonstrating that fasciculations persisted after nerve block in ALS and ceased only with the appearance of brillation potentials, signifying wallerian (axonal) degeneration These observations favored a distal site of generation.

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